日本語で表示
Faculty Members
Faculty of Biotechnology / Department of Bioscience Associate Professor

Kurokawa Yoichi

Profile Research Interest Selected Publications Social Activities Educational Activies Additional Information

Profile

AffiliationFaculty of Biotechnology / Department of Bioscience
TitleAssociate Professor
RoomFaculty of Biotechnology320 (Extension 3320)
E-mailkurokawa at fpu.ac.jp ( at = @ )
EducationGraduate School of Agriculture, Kyoto University
Academic Societies

Japan Society for Bioscience, Biotechnology, and Agrochemistry, The Japanese Biochemical Society, Protein Science Socity of Japan, The VItamin Society of Japan, Japan Applied Microbiolgy Society

Career

1996-2000 HSP Research Institute, Post-doctoral researcher
2000 Fukui Prefectural University, Assistant Professor
2007 Present position

Research Interest

Research FieldBiochemistry, Enzyme chemistry, Protein science
Research Summary

Investigation of molecular basis for abonormal protein formation, and its application

Heterologous production of human protein causative of a nervous disease, and exploration of chemicals that can prevent abnormal poduct of the protein

Keywordsstress response, abnormal protein, oxidative stress, antioxidant

Selected Publications

Overexpression of Bacterial Protein Disulfide Isomerase (DsbC) and Its Modulator Protein (DsbD) Markedly Enhances Periplasmic Production of Human Nerve Growth Factor in Escherichia coli.
Journal of Biological Chemistry 276. 14393-14399 (2001)

Combination of Dsb coexpression and an addition of sorbitol markedly enhanced soluble expression of single-chain Fv in Escherichia coli.Biotechnol Bioeng. 91(4):418-24. (2005)

The functional effect of Gly209 and Ile213 substitutions on lysozyme activity of family 19 chitinase encoded by cyanophage Ma-LMM01 Fisheries Science 77 (4):665-70. (2011)

Social Activities

Japan Society for Bioscience, Biotechnology, and Agrochemistry, The Japanese Biochemical Society, Protein Science Socity of Japan, The VItamin Society of Japan

Educational Activies

ClassesChemistry II, Biopolymer Chemistry, Experiments of Chemistry, Laboratory Course in Physical Biochemistry, Laboratory Course in Functional and Analytical Food Science
Available Topics

Efficient expression system for useful heterologous protein
How protein abnormalizes, and becomes a causative of a disease
Oxidation of protein under oxidative stress
Molecular aspects of function of chemicals of food-origin, especially vitamins and polyphenols

Additional Information

I am interested to know how proteins, functional biomolecules, are abnormalized and the charecteristics of the abnormalized proteins, in order to contribute to promote human health. Molecular aspects on the interaction of protein and chemicals are also of my great interest.

↑