特別セミナー(2012/6/28)

生物資源学特別セミナー

(後援: 科研費新学術領域生合成マシナリー)

 

演題: Genomics-inspired discovery and engineering of natural product drugs

演者: Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Science, UCSD, Prof. Bradley S. Moore

 

Natural product chemicals have historically been discovered based on their molecular and biological properties. With the ease and affordability of genome sequencing today, a new era in natural product discovery is unfolding in which genomics and biosynthesis are together fostering new innovations in compound discovery. This orthogonal discovery approach takes advantage of the biosynthetic potential of a genome-sequenced organism to design hypothesis-driven experiments to uncover new chemical entities. Examples from the author’s laboratory involving the anticancer agents salinosporamide and didemnin will highlight the myriad of available and evolving genome mining approaches to new natural product chemistry and biosynthetic enzymology.

 

日時: 平成24年6月28日(火)  16:30~18:00

場所: 生物資源学部棟 一階会議室

連絡先: 濱野吉十(内3408)

 

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