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Mizutani, Tetsuya
- Profile
- Research Interest
- Selected Publications
- Social Activities
- Educational Activies
- Additional Information
Profile
Research Interest
Research Field | Molecular Endocrinology, Reproductive biology, Gynecologic oncology, Epigenetics |
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Research Summary | 1, Analysis of molecular mechanisms by which gonadotropin induces ovarian development and differentiation. 2, Study on the mechanisms of cytotrophoblast differentiation into either syncytiotrophoblast or extravillous trophoblast. 3, Development of diagnostic biomarkers to distinguish uterine sarcomas from leiomyomas. |
Keywords | Ovary, Placenta, Differentiation, Transcriptional regulation, Uterine sarcoma |
Selected Publications
【Review】
・「Transcriptional regulation of genes related to progesterone production」Endocr J 2015
・「Identification of novel steroidogenic factor 1 (SF-1)-target genes and components of the SF-1 nuclear complex」Mol Cell Endocrinol 2015
【Article】
・「Establishment and characterization of a novel orthotopic mouse model for human uterine sarcoma with different metastatic potentials」Cancer Lett 2015
・「C/EBPβ (CCAAT/enhancer-binding protein β) mediates progesterone production through transcriptional regulation in cooperation with SF-1 (steroidogenic factor-1)」Biochem J 2014
・「Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis」FASEB J 2013
・「Nuclear receptor 5A (NR5A) family regulates 5-aminolevulinic acid synthase 1 (ALAS1) gene expression in steroidogenic cells」Endocrinology 2012
・「Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1 dependent chromatin architecture」J Biol Chem 2010
Community Engagement
Committee Member of The Japan Endocrine Society
Committee Member of Japan Society of Reproductive Endocrinology
Educational Activites
Classes | Anatomy and Physiology I Anatomy and Physiology II Graduation Study |
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Office Hour | |
Available Topics | Ovary, Placenta, Transcriptional regulation, Epigenetics |
Additional Information
Awards:
2015 Research Award (The Japan Endocrine Society)
2001 Young investigator awards (The Japan Endocrine Society)
2001 Young scientist awards (Japan Society of Reproductive Endocrinology)