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Yokoyama Yoshihiro

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Affiliation Faculty of Marine Science and Technology / Department of Marine Bioscience
Title Professor
Room Faculty of Marine Science and Technology 605 (Extension1605)
E-mail yokoyama ( at = @ )
Website
Education PhD, Kyoto Univ.
Degree
Academic Societies The Japanese Society of Fisheries Science (Soc. prize 1996), 1985-; Japan Society of Nutrition and Food Science, 1987-; The Japanese Biochemical Society, 1997-; The Molecular Biology Society of Japan, 1997-; Japanese Traditional Food Workshop, 2000-; The Japanese Society of Food Engineering, 2010-
Career Rschr. Interdisciplinary Rsch. Inst. Environ. Sci., Kyoto, 1987-96; asst. Mukogawa Women's U., Nishinomiya, Hyogo, 1996-2000; assoc. prof. Kobe Shoin Women's Coll., Kobe, Hyogo, 2000-02;
assoc. prof. Fukui Prefectural U., Obama, Fukui, 2002-08;
prof., Fukui Prefectural U., Obama, Fukui, Japan, 2008-.

Research Interest

Research Field Food chemistry
Research Summary 1) Postmortem biochemical changes in fish and shellfish, 2) Molecular studies on fish and shellfish collagens, and 3) Studies on bioactive substances and effective utilization in marine unused bioresources.
Keywords stress protein, transportation-stress, hypoxia, heatshock, collagen, collagens modifying enzyme, jellyfish, effective utilization, marine bioresources

Selected Publications

Effects of immersion salinity on the food properties of shucked oysters. Fish. Sci.(2014)
Cloning and expression of cDNA encoding lysyl hydroxylase 1, 2 and 3 in tiger puffer Takifugu rubripes. Comp. Biochem. Physiol. B. (2013)
Purification and characterization of a lectin from the starfish Asterias amurensis. Fish. Sci. (2013)
Isolation of collagen from tiger pufferfish parts and its solubility in dilute acetic acid. Fish. Sci. (2013)
Enzymatic solubilization of collagen in the skin of diamond squid Thysanoteuthis rhombus: application of a fungal acid protease. Fish. Sci.(2013)
Existence of a 400 kDa glycoprotein in the dermis of sea cucumber Apostichopus armata: partial purification and characterization. Fish. Sci. (2013)
Role of hypoxia-inducible factor α in response to hypoxia and heat shock in the Pacific oyster Crassostrea gigas. Mar. Biotechnol. (2012)
Molecular species of collagen in muscular and vertebral parts of white sturgeon Acipenser transmontanus. Fish. Sci. (2012)
Novel isoforms of heat shock transcription factor 1 are induced by hypoxia in the Pacific oyster, Crassostrea gigas. J. Exp. Zool. A, (2011).
Historical progression in products of Wakasa Kodai. Quest for Traditional Food, (2010).
Biochemical changes in oyster tissues and hemolymph during long-term air exposure, Fisheries Sci. (2010) .
Molecular cloning of calnexin and calreticulin in the Pacific oyster Crassostrea gigas and its expression in response to air exposure. Marine Genomics, (2010).
Purification, characterization and cDNA cloning of a novel lectin from the jellyfish Nemopilema nomurai.Comp. Biochem. Physiol. B, (2010).
cDNA cloning and expression of grp94 in the Pacific oyster Crassostrea gigas. Comp. Biochem. Physiol. B, 154 (2009).
Cell growth promoting activity of fluid from eye sacs of bubble-eye goldfish (Carassius auratus). Zool. Sci., 26 (2009).
Hot-water solubility of mantle collagens in several cephalopod molluscs. Fishe. Scie., 75 (2009).
cDNA cloning and characterization of Type V/XI procollagen a1 chain in the skate Raja kenojei. Food Chem., 107 (2008).
Expression and distribution of fugu TIMP-2s (fgTIMP-2a and fgTIMP-2b) mRNAs in tissues and embryos. Comp. Biochem. Physiol. B, 148 (2007).
Molecular cloning and expression of gelatinases (MMP-2 and MMP-9) in the fugu Takifugu rubripes. Comp. Biochem. Physiol. B, 148 (2007).
Properties of scallop mantle collagen: its content, tissue distribution, and thermal behavior. Fish. Sci., 73 (2007).
Purification and characterization of molecular species of collagen in tha skin of skate (Raja kenojei). Food Chem., 100 (2007).
Expression of fugu TIMP-3 and -4 genes in adult tissues and embryos. Comp. Biochem. Physiol. B, 144 (2006).
cDNA cloning and characterization of Type II procollagen a1 chain in the skate Raja kenojei. J. Fish. Sci. Technol., 9 (2006).
cDNA cloning and characterization of Type I procollagen a1 chain in the skate Raja kenojei. Comp. Biochem. Physiol. B 144 (2006).
cDNA cloning of Japanese oyster stress protein homologous to the mammalian 78-kDa glucose regulated protein (GRP78) and its induction by heatshock. Fish. Sci, 72 (2006).
Expression of hsp70 responding to heat-shock and its cDNA cloning from Mediterranean blue mussel. Fish. Sci.,(2005).
Occurrence of Two Distinct Types of Tissue Inhibitors of Metalloproteinases-2 in Fugu rubripes. J. Ocean Univ. China, 4(3) (2005).
Occurrence of Two Distinct Types of Tissue Inhibitors of Metalloproteinases-2 in Fugu rubripes. Proceeding of 9th International Symposium on Efficient Application and Preservation of Marine Biological Resources, (2004).
Occurrence of two distinct types of tissue inhibitor of metalloproteinases-2 （TIMP-2） in teleost fish．Biochim． Biophys． Acta.,1629 （2003）.
cDNA cloning and characterization of HSP70 family in Japanese oyster. Proceeding of 8th International Symposium on Efficient Application and Preservation of Marine Biological Resources （2003）.
cDNA cloning and characterization of GRP78/Bip in Japanese oyster Crassostrea gigas. TUF International JSPS Project, 14 （2003）.
The nuclear export signal （NES） found in the amino-terminal region of carp MEK1 and MKK6 is lacking in carp MKK4. Biophys. Acta.,1575 （2002）.
Complementary DNA cloning of HSC71, a 71 kDa heat shock cognate protein, in Japaneses oyster Crassostrea gigas. Review Living Sci., 33 （2002）.
Japanese flounder reversed, displays a randomization of metamorphic and visceral left-right asymmetries without correlation. Fisheries Sci, 68（2002).
Cloning and expression of two types of tissue inhibitor of metalloproteinase 2 from Japanese flounder. Fisheries Sci, 68 （2002）.
Isolation and characterization of a Japanese flounder clone line, reserved, which exhibits reversal of metamorphic left-right asymmetry. Mech. Develop., 111 （2002）.
Sequence and structure of Japanese flounder （Paralichtys olivaceus） mitochondrial genome. Bul.TohokuNational Fish. Res. Inst., 64 （2001）.
Structure of a full a full-length cDNA clone for the pro-a1 （V/XI） collagen chain of red sebream. Biochim. Biophys. Acta., 1517 （2001）.
Structure and expression of oyster polypeptide chain elongation factor 1α. Review Living Sci.,32 （2001）.
Phosphorylation status and function of p53 areinversely related to protein kinase c activation. Anticancer Res., 20 （2000）.
Identificationof a nuclear export signal in MKK6, an activator of the carp p38 mitogen-activated protein kinases.Eur. J. Biochem., 19 （2000）
Complete nucleotidesequence of Jpanese flounder （Paralichtys olivaceus） mitochondrial genome: structural property andcue for resolving teleostean relationships. J. Heredity, 91 （2000）.
Induction of gelatinolytic activities in ayu muscle at spawning stage. Fish. Sci., 66 （2000）

Community Engagement

Educational Activities

Classes Technology for Utilization of Marine Bioresources, Nutritional Science of Food, Introduction to Marine Bioscience, Regional Seminar course A, Introductory Fieldwork in Marine Bioscience, Experiments in Chemistry, Laboratory Course in Food Chemistry, Scien
Office Hour
Available Topics Mechanism in the stress response of bivalves.
Collagen and its modifying enzymes of fish.
Effective utilization of components derived from marine organisms.

Additional Information