原著論文(2000~2018)

1. Murakami S, Ono A, Kawasaki A, Takenaga T, Ito T. Taurine attenuates the development of hepatic steatosis through the inhibition of oxidative stress in a model of nonalcoholic fatty liver disease in vivo and in vitro. Amino Acids. 2018 Jun 26. doi: 10.1007/s00726-018-2605-8.
2. Ito T, Nakanishi Y, Yamaji N, Murakami S, Schaffer SW. Induction of Growth Differentiation Factor 15 in Skeletal Muscle of Old Taurine Transporter Knockout Mouse. Biol Pharm Bull. 2018;41(3):435-439. doi: 10.1248/bpb.b17-00969.
3. Ito T, Okazaki K, Nakajima D, Shibata D, Murakami S, Schaffer S. Mass spectrometry-based metabolomics to identify taurine-modified metabolites in heart. Amino Acids, 2018;50(1):117-124. doi: 10.1007/s00726-017-2498-y.
4. Kawasaki A, Ono A, Mizuta S, Kamiya M, Takenaga T, Murakami S. The Taurine Content of Japanese Seaweed. Adv Exp Med Biol. 975, 1105-1112 (2017)
5. Murakami S. The physiological and pathophysiological roles of taurine in adipose tissue in relation to obesity. Life Sci., 186, 80-86 (2017)
6. Murakami S. The physiological and pathophysiological roles of taurine in adipose tissue in relation to obesity. J Nutr Sci Vitaminol (Tokyo). 2017;63(3):193-199.Life Sci., 186, 80-86 (2017)
7. Kawabata K, Kitamura K, Irie K, Naruse S, Matsuura T, Uemae T, Taira S, Ohigashi H, Murakami S, Takahashi M, Kaido Y, Kawakami B. Triterpenoids Isolated from Ziziphus jujuba Enhance Glucose Uptake Activity in Skeletal Muscle Cells. J Nutr Sci Vitaminol (Tokyo), 63, 193-199 (2017)
8. Iwase M, Yamamoto T, Nishimura K, Takahashi H, Mohri S, Li Y, Jheng HF, Nomura W, Takahashi N, Kim CS, Yu R, Taniguchi M, Baba K, Murakami S, Kawada T, Goto T, Suksdorfin Promotes Adipocyte Differentiation and Improves Abnormalities in Glucose Metabolism via PPARγ Activation. Lipids 52, 657-664 (2017).
9. Murakami S, Fujita M, Nakamura M, Sakono M, Nishizono S, Sato M, Imaizumi K, Fukuda N, Taurine ameliorates cholesterol metabolism by stimulating bile acid production in high-cholesterol-fed rats. Clin Exp Pharmacol Physiol 43, 372-8 (2016).
10. Li Y, Goto T, Yamakuni K, Takahashi H, Takahashi N, Jheng HF, Nomura W, Taniguchi M, Baba K, Murakami S, Kawada T, 4-Hydroxyderricin, as a PPARγ agonist, promotes adipogenesis, adiponectin secretion, and glucose uptake in 3T3-L1 cells. Lipids 51, 787-95 (2016).
11. Li Y, Goto T, Ikutani R, Lin S, Takahashi N, Takahashi H, Jheng HF, Yu R, Taniguchi M, Baba K, Murakami S, Kawada T, Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring) 24, 2351-2360 (2016).
12. 平修，川崎安都紗，小野鮎子，片野肇，村上茂，イメージング質量分析によるタウリンの体内動態分析，タウリンリサーチ 2, 12-15 (2016).
13. 小野鮎子，川崎安都紗，高橋正和，村上茂，タウリンの肝細胞脂肪蓄積抑制作用，タウリンリサーチ 2, 22-24 (2016).
14. 川崎安都紗，小野鮎子，水田尚志，神谷充伸，村上茂，海藻中のタウリン含量の分析，タウリンリサーチ 2, 25-27 (2016).
15. 村上茂，肥満におけるタウリン役割，タウリンリサーチ 2, 34-36 (2016).
16. Sagara M, Murakami S, Mizushima S, Liu L, Mori M, Ikeda K, Nara Y, Yamori Y, Taurine in 24-hour urine is inversely related to cardiovascular risks in middle aged subjects of 50 populations in the world. Adv Exp Med Biol 803, 623-636 (2015).
17. 高橋正和、村上茂、久保義人、小林恭一 福井県産ウメ抽出物ならびにエゴマ油成分の肝細胞脂肪蓄積抑制作用の検討、福井県立大学論集 45, 47-55 (2015).
18. 村上茂 タウリン研究と産業利用の歴史、タウリンリサーチ 1, 7-8 (2015).
19. 家森幸男、森真理、相良未木、村上茂 タウリン研究のモデルから世界への展開、タウリンリサーチ 1, 12-15 (2015).
20. 西園祥子、福田亘博、村上茂 タウリン食ラット肝臓におけるコレステロールエステルの蓄積・分泌低下と脂肪酸酸化の関係、タウリンリサーチ 1, 50-52 (2015).
21. Abe Y, Ohkuri T, Yoshitomi S, Murakami S, Ueda T, Role of osmolyte taurine on the folding of a model protein, hen egg white lysozyme, under a crowded condition. Amino Acids 47, 909-915 (2015).
22. Sagara M, Murakami S, Mizushima S, Liu L, Mori M, Ikeda K, Nara Y, Yamori Y, Taurine in 24-hour urine is inversely related to cardiovascular risks in middle aged subjects of 50 populations in the world. Adv Exp Med Biol 803, 623-636 (2015).
23. 村上茂 タウリン研究と産業利用の歴史、タウリンリサーチ 1, 7-8 (2015).
24. 家森幸男、森真理、相良未木、村上茂 タウリン研究のモデルから世界への展開、タウリンリサーチ 1, 12-15 (2015).
25. 西園祥子、福田亘博、村上茂 タウリン食ラkツト肝臓におけるコレステロールエステルの蓄積・分泌低下と脂肪酸参加の関係、タウリンリサーチ 1, 50-51 (2015).
26. Lin S, Hirai S, Yamaguchi Y, Goto T, Takahashi N, Tani F, Mutoh C, Sakurai T, Murakami S, Yu R, Kawada T, Taurine improves obesity-induced inflammatory responses and modulates the unbalanced phenotype of adipose tissue macrophages. Mol Nutr Food Res 57, 2155-2165 (2013).
27. Takahashi N, Senda M, Lin S, Goto T, Yano M, Sasaki T, Murakami S, Kawada T. Auraptene regulates gene expression involved in lipid metabolism through PPAR activation in diabetic obese mice.Mol Nutr Food Res 55, 1791-1797 (2011).
28. Goto T, Nagai H, Egawa K, Kim Y-Il, Kato S, Taimatsu A, Sakamoto T, Ebisu S, Hosaka T, Miyagawa H, Murakami S, Takahashi N, Kawada T, Farnesyl pyrophosphate regulates adipocyte function as an endogenous PPARγ agonist. Biochem J 438, 111-119 (2011).
29. Fukuda N, Yoshitama A, Sugita S, Fujita M, Murakami S. Taurine reduces hepatic secretion of cholesteryl ester and enhances fatty acid oxidation in rats fed a high-cholesterol diet. J Nutr Sci Vitaminol 57, 144-149 (2011).
30. Murakami S, Sakurai T, Toda Y, Morito A, Sakono M, Fukuda N, Prevention of neointima formation by taurine ingestion after carotid balloon injury. Vascul Pharmacol 53, 177-184 (2010).
31. Nagao K, Yamano N, Shirouchi B, Inoue N, Murakami S, Sasaki T, Yanagita T, Effect of citrus auraptene (7-geranyloxycoumarine) on hepatic lipid metabolism in vitro and in vivo. J Agric Food Chem 58, 9028-9032 (2010).
32. Murakami S, Sakurai T, Tomoike H, Sakono M, Nasu T, Fukuda N, Prevention of hypercholesterolemia and atherosclerosis in the hyperlipidemia- and atherosclerosis-prone Japanese (LAP) quail by taurine supplementation. Amino Acids 38, 271-278 (2009).
33. Ando C, Takahashi N, Hirai S, Nishimura K, Lin S, Uemura T, Goto T, Yu R, Nakagami J, Murakami S, Kawada T, Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation. FEBS Lett 583, 3649-3654 (2009).
34. Yamori Y, Liu L, Mori M, Sagara M, Murakami S, Nara Y, Mizushima S, Taurine as the nutritional factor for the longevity of the Japanese revealed by a world-wide epidemiological survey. Adv Exp Med Biol 643, 13-25 (2009).
35. Takahashi N, Kang MS, Kuroyanagi K, Goto T, Hirai S, Ohyama K, Lee JY, Yu R, Yano M, Sasaki T, Murakami S, Kawada T, Auraptene, a citrus fruit compound, regulates gene expression as a PPAR alpha agonist in HepG2 hepatocytes. Biofactors 33, 25-32 (2008).
36. Yanagita T, Han SY, Hu Y, Nagao K, Kitajima H, Murakami S, Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells. Lipids Health Dis 7, 38-43 (2008).
37. Kato J, Ido A, Uto H, Hori T, Hayashi K, Murakami S, Terano A, Tsubouchi H, Tranforming growth factor-beta-induced stimulation of collagen fiber network and anti-fibrotic effect of taurine in an in vitro model of hepatic fibrosis. Hepatol Res 30, 34-41 (2004).
38. Murakami S, Takashima H, Saitoh M, Sato-Watanabe M, Chonan S, Yamamoto K, Saito S, Yoshimura H, Sugawara K, Yang J, Gao N, Zhang X, Ursolic acid, an antagonist for TGF-beta. FEBS Lett 566, 55-59 (2004).
39. Yamori Y, Murakami S, Ikeda K, Nara Y, Fish and life-related disease prevention: experimental and epidemiological evidence for anti-atherogenic potential of taurine. Clin Exp Pharmacol Physiol 31, (Suppl 2) S20-S23 (2004).
40. Terui Y, Yiwen C, Jun-ying L, Ando T, Yamamoto H, Kawamura Y, Tomishima Y, Uchida S, Okazaki T, Munetomo E, Seki T, Yamamoto K, Murakami S, Kawashima A, Xantholipin, a novel inhibitor of HSP47 gene expression produced by Streptomyces sp. Tetrahedron Lett 44, 5427-5430 (2003).
41. Yoshimura H, Sugawara K, Saito M, Saito S, Murakami S, Miyata N, Kawashima A, Morimoto S, Gao N, Zhang X, Yang J, In vitro TGF-beta antagonistic activity of ursolic and oleanolic acids isolated from Clerodendranthus spicatus. Planta Med 69, 673-675 (2003).
42. Matsushima Y, Sekine T, Kondo Y, Sakurai T, Kameo K, Tachibana M, Murakami S, Effects of taurine on serum lipoproteins and development of atherosclerosis in spontaneously hyperlipidemic (SHL) mice. Clin Exp Pharmacol Physiol 30, 295-299 (2003).
43. Watarai M, Makino S, Michikawa M, Yanagisawa K, Murakami S, Shirahata T, Macrophage plasma membrane cholesterol contributes to Brucella abortus infection of mice. Infect Immun 70, 4818-4825 (2002).
44. Murakami S, Kondo Y, Kitajima H, Nagate T, Taurine suppresses development of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) rabbits. Atherosclerosis 163, 79-87 (2002).
45. Kondo Y, Toda Y, Kitajima H, Oda H, Nagate T, Kameo K, Murakami S, Taurine inhibits the development of atherosclerotic lesions in apolipoprotein E-deficient mice. Clin Exp Pharmacol Physiol 28, 809-815 (2001).
46. Chino Y, Minagawa T, Kohno Y, Toda Y, Murakami S, Higuchi S, Uptake by vascular smooth muscle cells plays an important role in targeting of lipid microspheres incorporating prostaglandin E1 into a thickened intima. Life Sci 68, 933-942 (2001).
47. Murakami S, Toda Y, Seki T, Munetomo E, Kondo Y, Sakurai T, Ohtsuka Y, Matsuyama M, Nagate T, Hosokawa N, Nagata K, Heat shock protein (HSP) 47 and collagen are up-regulated during neointimal formation in the balloon-injured rat carotid artery. Atherosclerosis 157, 361-368 (2001).
48. Yamamoto K, Yoshitama A, Sakono M, Nasu T, Murakami S, Fukuda N, Dietary taurine decreases hepatic secretion of cholesterol ester in rats fed a high-cholesterol diet. Pharmacology 60, 27-33 (2000).

総説

1. Murakami S, Role of taurine in the pathogenesis of obesity. Mol Nutr Food Res 59, 1353-1363 (2015).
2. Murakami S, Taurine and atherosclerosis. Amino Acids 46, 73-80 (2014).
3. Imae M, Asano T, Murakami S, Potential role of taurine in the prevention of diabetes and metabolic syndrome. Amino Acids 46, 81-88 (2014).
4. 村上 茂 脳卒中易発症高血圧ラット（SHRSP）におけるタウリンの脂質低下改善作用、日本農芸化学会誌 75, 972-975 (2001).

著書

1. 村上茂 北陸路に棗ありて、薬理作用総論p67-85 金森昌彦 編集 三恵社、2017年
2. 村上茂 監修・著、読んで効くタウリンのはなし、成山堂、2016年
3. 高橋正和、村上茂、片野肇、村上亜由美、小林恭一、橋本直哉、天谷美都希、久保義人、福井県産農作物の機能性解析と機能性成分の効率的精製法 食品と開発、50巻、11号、73-76 2015年
4. Murakami S, Yamori Y, Taurine and longevity- Preventive effect of taurine on metabolic syndrome. In Bioactive food as dietary interventions for the aging population. Edited by Watson RR and Preedy VR, Academic Press/Elsevier, San Diego USA (2012).
5. Murakami S, Kondo Y, Nagate T, Effects of long-term treatment with taurine in mice fed a high-fat diet. In Taurine 4- Taurine and excitable tissues-, Kluwer Academic/Plenum Publishers, New York, 177-186 (2000).
6. Kondo Y, Murakami S, Oda H, Nagate T, Taurine reduces atherosclerotic lesion development in apolipoprotein E-deficient mice. . In Taurine 4- Taurine and excitable tissues-, Kluwer Academic/Plenum Publishers, New York, 193-202 (2000).