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吉浦 康寿よしうら やすとし
プロフィール
研究活動
| 専門 | 魚類育種学 魚類生理学 |
|---|---|
| 研究活動の紹介 | これまで魚類の繁殖、性分化、免疫について幅広く研究をしてきました。この経験をもとに、約10年前から新しい品種改良技術としてTILLING法（植物で開発された品種改良技術）、ゲノム編集を養殖魚の品種改良の導入し、肉厚なトラフグ、高成長なトラフグを作り出すことに成功しました。また、これらの魚と天然魚との遺伝子交雑を防ぐための不妊化技術の開発もあわせて進めています。今後は、これらの技術を多くの魚介類でも利用できるように基礎から応用まで広範囲に研究を行います。 |
| キーワード | ゲノム編集、突然変異育種、品種改良、高産肉性、高成長、不妊化、メダカ、トラフグ |
著書・論文
著書
フグ食の科学
酒井, 治己 (担当:分担執筆, 範囲:トラフグの育種技術ーバイオテクノロジーをフグ養殖へ利用する)
生物研究社 2021年 (ISBN: 9784909119193)
ゲノム編集食品 : 農林水産分野への応用と持続的社会の実現
田部井, 豊 (担当:分担執筆, 範囲:養殖魚でのゲノム編集 －肉厚マダイ・トラフグの作出を例に)
エヌ・ティー・エス 2021年 (ISBN: 9784860437169)
よくわかる! 種苗生産と育種
(担当:分担執筆, 範囲:TILLING法を用いたトラフグ優良品種作出技術)
緑書房 2014年
Aquatic genomics : steps toward a great future
清水, 信義, 青木, 宙, 廣野, 育生, 隆島, 史夫 (担当:分担執筆, 範囲:The GnRH system in teleosts)
Springer 2003年 (ISBN: 4431703314)
Eel biology
会田, 勝美, 塚本, 勝巳, 山内, 晧平 (担当:分担執筆, 範囲:GTH and GnRH Molecules and Their Expression in the Japanese Eel)
Springer 2003年 (ISBN: 4431004580)
2010年以降の論文
Roles of Gonadotropin Receptors in Sexual Development of Medaka
Takeshi Kitano, Tomoaki Takenaka, Hisanori Takagi, Yasutoshi Yoshiura, Yukinori Kazeto, Toshiaki Hirai, Koki Mukai, Ryo Nozu
Cells 11(3) 387-387 2022年
Induction of germ cell-deficiency in grass puffer by dead end 1 gene knockdown for use as a recipient in surrogate production of tiger puffer
Hiroyuki Yoshikawa, Yasuko Ino, Kenta Kishimoto, Hayato Koyakumaru, Taiju Saito, Masato Kinoshita, Yasutoshi Yoshiura
AQUACULTURE 526 2020年
Development of an enzyme-functionalized immunosensor for measuring maturation-inducing hormone in fish
Haiyun Wu, Yusuke Saito, Yasutoshi Yoshiura, Hitoshi Ohnuki, Hideaki Endo
BIOCHEMICAL ENGINEERING JOURNAL 154 2020年
Development of a Novel Enhanced Biosensor System for Real-Time Monitoring of Fish Stress Using a Self-Assembled Monolayer
Wu, Haiyun, Fujii, Yuzu, Nakano, Toshiki, Arimoto, Takafumi, Murata, Masataka, Matsumoto, Haruto, Yoshiura, Yasutoshi, Ohnuki, Hitoshi, Endo, Hideaki
SENSORS 19(7) 2019年
Novel method for mass producing genetically sterile fish from surrogate broodstock via spermatogonial transplantation
Nagasawa, Kazue, Ishida, Mariko, Octavera, Anna, Kusano, Kazunari, Kezuka, Fumi, Kitano, Takeshi, Yoshiura, Yasutoshi, Yoshizaki, Goro
BIOLOGY OF REPRODUCTION 100(2) 535-546 2019年
An effective microinjection method for genome editing of marine aquaculture fish: tiger pufferfish Takifugu rubripes and red sea bream Pagrus major
Kishimoto, Kenta, Washio, Youhei, Murakami, Yu, Katayama, Takashi, Kuroyanagi, Miwa, Kato, Keitaro, Yoshiura, Yasutoshi, Kinoshita, Masato
FISHERIES SCIENCE 85(1) 217-226 2019年
Production of a breed of red sea bream Pagrus major with an increase of skeletal muscle mass and reduced body length by genome editing with CRISPR/Cas9
Kishimoto, Kenta, Washio, Youhei, Yoshiura, Yasutoshi, Toyoda, Atsushi, Ueno, Tomohiro, Fukuyama, Hidenao, Kato, Keitaro, Kinoshita, Masato
AQUACULTURE 495 415-427 2018年
Production of tiger puffer Takifugu rubripes from cryopreserved testicular germ cells using surrogate broodstock technology
Hiroyuki Yoshikawa, Yasuko Ino, Kouhei Shigenaga, Takashi Katayama, Miwa Kuroyanagi, Yasutoshi Yoshiura
AQUACULTURE 493 302-313 2018年
Ultra highly sensitive method for detecting Edwardsiella ictaluri using high-gradient immunomagnetic separation with polymerase chain reaction
Haiyun Wu, Kobeni Sugata, Mutsuko Hirai, Yasutoshi Yoshiura, Kyoko Hibi, Hideaki Endo
Sensing and Bio-Sensing Research 16 68-73 2017年1
水産育種へのゲノム編集技術の応用と課題
岸本謙太, 鷲尾洋平, 豊田 敦, 吉浦康寿, 家戸敬太郎, 木下政人
DNA鑑定 9 45-50 2017年
Development of an optical communication type biosensor for real-time monitoring of fish stress
Shinoda, Ryosuke, Wu, Haiyun, Murata, Masataka, Ohnuki, Hitoshi, Yoshiura, Yasutoshi, Endo, Hideaki
SENSORS AND ACTUATORS B-CHEMICAL 247 765-773 2017年
Comprehensive validation of T- and B-cell deficiency in rag1-null zebrafish: Implication for the robust innate defense mechanisms of teleosts
Tokunaga, Yumie, Shirouzu, Masamichi, Sugahara, Ryota, Yoshiura, Yasutoshi, Kiryu, Ikunari, Ototake, Mitsuru, Nagasawa, Takahiro, Somamoto, Tomonori, Nakao, Miki
SCIENTIFIC REPORTS 7(1) 7536-7536 2017年
New approach for monitoring fish stress: A novel enzyme-functionalized label-free immunosensor system for detecting cortisol levels in fish
Wu, Haiyun, Ohnuki, Hitoshi, Ota, Shirei, Murata, Masataka, Yoshiura, Yasutoshi, Endo, Hideaki
BIOSENSORS & BIOELECTRONICS 93 57-64 2017年
Effective removal of residual sperm from rearing tank using a foam separation device
Tadashi Imai, Yasutoshi Yoshiura, Toshinori Takashi, Tetsuo Morita, Satoshi Imai, Yoshihisa Yamamoto, Masakazu Oka
Aquaculture Science 65(2) 145-147 2017年
Growth control of juvenile tiger puffer Takifugu rubripes by water temperature adjustment for efficient selection using the TILLING method
Tadashi Imai, Takashi Katayama, Yousuke Kagawa, Yoshihisa Yamamoto, Yasutoshi Yoshiura
Aquaculture Science 65(1) 41-50 2017年
ミトコンドリアDNA解析から推定する香川県メダカの集団史
山下佳那, 勝村啓史, 尾田正二, 今井正, 吉浦康寿, 太田博樹
地域自然史と保全 38(1) 41-50 2016年
TALENs-mediated gene disruption of myostatin produces a larger phenotype of medaka with an apparently compromised immune system
Chiang, Yi-An, Kinoshita, Masato, Maekawa, Shun, Kulkarni, Amod, Lo, Chu-Fang, Yoshiura, Yasutoshi, Wang, Han-Ching, Aoki, Takashi
FISH & SHELLFISH IMMUNOLOGY 48 212-220 2016年
Homologue gene of bile acid transporters ntcp, asbt, and ost-alpha in rainbow trout Oncorhynchus mykiss: tissue expression, effect of fasting, and response to bile acid administration
Murashita, Koji, Yoshiura, Yasutoshi, Chisada, Shin-ichi, Furuita, Hirofumi, Sugita, Tsuyoshi, Matsunari, Hiroyuki, Iwashita, Yasuro, Yamamoto, Takeshi
FISH PHYSIOLOGY AND BIOCHEMISTRY 40(2) 511-525 2014年
Potential infectivity of the virus re-isolated from surviving Japanese amberjack (Seriola quinqueradiata) after experimental infection with red sea bream iridovirus
Ito, T., Kawato, Y., Yoshiura, Y., Kamaishi, T., Yoshida, K., Nakajima, K.
BULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS 34(1) 17-24 2014年
Design, evaluation, and screening methods for efficient targeted mutagenesis with transcription activator-like effector nucleases in medaka
Ansai, Satoshi, Inohaya, Keiji, Yoshiura, Yasutoshi, Schartl, Manfred, Uemura, Norihito, Takahashi, Ryosuke, Kinoshita, Masato
DEVELOPMENT GROWTH & DIFFERENTIATION 56(1) 98-107 2014年
Leptin receptor-deficient (knockout) medaka, Oryzias latipes, show chronical up-regulated levels of orexigenic neuropeptides, elevated food intake and stage specific effects on growth and fat allocation
Chisada, Shin-ichi, Kurokawa, Tadahide, Murashita, Koji, Ronnestad, Ivar, Taniguchi, Yoshihito, Toyoda, Atsushi, Sakaki, Yoshiyuki, Takeda, Shunichi, Yoshiura, Yasutoshi
GENERAL AND COMPARATIVE ENDOCRINOLOGY 195 9-20 2014年
New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis
Miwa Kuroyanagi, Takashi Katayama, Tadashi Imai, Yoshihisa Yamamoto, Shin-ichi Chisada, Yasutoshi Yoshiura, Tomokazu Ushijima, Tomonao Matsushita, Masashi Fujita, Aoi Nozawa, Yuzuru Suzuki, Kiyoshi Kikuchi, Hiroyuki Okamoto
BMC GENOMICS 14 786-786 2013年
Postprandial response and tissue distribution of the bile acid synthesis-related genes, cyp7a1, cyp8b1 and shp, in rainbow trout Oncorhynchus mykiss
Koji Murashita, Yasutoshi Yoshiura, Shin-ichi Chisada, Hirofumi Furuita, Tsuyoshi Sugita, Hiroyuki Matsunari, Takeshi Yamamoto
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 166(2) 361-369 2013年
Prevalence of red sea bream iridovirus among organs of Japanese amberjack (Seriola quinqueradiata) exposed to cultured red sea bream iridovirus
Ito, Takafumi, Yoshiura, Yasutoshi, Kamaishi, Takashi, Yoshida, Kazunori, Nakajima, Kazuhiro
JOURNAL OF GENERAL VIROLOGY 94(Pt 9) 2094-2101 2013年
Adaptive immune response to Edwardsiella tarda infection in ginbuna crucian carp, Carassius auratus langsdorfii
Masatoshi Yamasaki, Kyosuke Araki, Teruyuki Nakanishi, Chihaya Nakayasu, Yasutoshi Yoshiura, Takaji Iida, Atsushi Yamamoto
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 153(1-2) 83-90 2013年
Dynamics of virus titer and quantity of red sea bream iridovirus DNA using natural and autoclaved artificial sea water under different water temperatures
T. Ito, Y. Yoshiura, T. Kamaishi, K. Nakajima
BULLETIN OF THE EUROPEAN ASSOCIATION OF FISH PATHOLOGISTS 33(4) 118-125 2013年
Ultra highly sensitive method for detecting Flavobacterium psychrophilum using high-gradient immunomagnetic separation with a polymerase chain reaction
Uni Ryumae, Kyoko Hibi, Yasutoshi Yoshiura, Huifeng Ren, Hideaki Endo
AQUACULTURE RESEARCH 43(6) 929-939 2012年
Rapid Detection of Flavobacterium psychrophilum Using Fluorescent Magnetic Beads and Flow Cytometry
Hibi, Kyoko, Yoshiura, Yasutoshi, Ushio, Hideki, Ren, Huifeng, Endo, Hideaki
SENSORS AND MATERIALS 24(6) 311-322 2012年
Myostatin-deficient medaka exhibit a double-muscling phenotype with hyperplasia and hypertrophy, which occur sequentially during post-hatch development
Chisada, Shin-ichi, Okamoto, Hiroyuki, Taniguchi, Yoshihito, Kimori, Yoshitaka, Toyoda, Atsushi, Sakaki, Yoshiyuki, Takeda, Shunichi, Yoshiura, Yasutoshi
DEVELOPMENTAL BIOLOGY 359(1) 82-94 2011年
Rapid and highly sensitive detection of Flavobacterium psychrophilum using high gradient immunomagnetic separation with flow cytometry
Uni Ryumae, Kyoko Hibi, Yasutoshi Yoshiura, Huifeng Ren, Hideaki Endo
AQUACULTURE 309(1-4) 125-130 2010年
突然変異育種を利用した養殖魚の効率的な新品種作出技術の開発について
吉浦康寿, 岡本裕之
水産育種 39(1) 1-7 2010年
それ以前の著書・論文はreserach mapを参照
https://researchmap.jp/yasutoshi
社会・地域活動
教育活動
| 担当科目 | 水族遺伝育種学、遺伝育種学実験 |
|---|---|
| オフィスアワー | 9時～17時 |
| 相談・講演・共同研究等に応じられるテーマなど | ゲノム編集等を用いた新しい養殖魚の品種改良について |