Mizutani, Tetsuya


Affiliation Graduate School & Faculty of Nursing and Social Welfare Science, Department of Nursing Science
Title Professor
Room N454 (Extension4454)
E-mail mizutani ( at = @ )
Education 1999 Ph.D. (Gunma University, Graduate School of Medicine)
Academic Societies
Career 2019- Professor, Fukui Prefectural University
2010- Associate Professor, University of Fukui
2007- Lecturer, University of Fukui
2005- Assistant Professor, University of Fukui
2003- Postdoctoral Scholar, The University of Iowa, College of Medicine
2000- Assistant Professor, Fukui Medical University
1999- Fellow of the Japan Society for the Promotion of Science for Japanese Junior Scientists

2019- Affiliate Professor, University of Fukui

Research Interest

Research Field Molecular Endocrinology, Reproductive biology, Gynecologic oncology, Epigenetics
Research Summary 1, Analysis of molecular mechanisms by which gonadotropin induces ovarian development and differentiation.
2, Study on the mechanisms of cytotrophoblast differentiation into either syncytiotrophoblast or extravillous trophoblast.
3, Development of diagnostic biomarkers to distinguish uterine sarcomas from leiomyomas.
Keywords Ovary, Placenta, Differentiation, Transcriptional regulation, Uterine sarcoma

Selected Publications

・「Transcriptional regulation of genes related to progesterone production」Endocr J 2015
・「Identification of novel steroidogenic factor 1 (SF-1)-target genes and components of the SF-1 nuclear complex」Mol Cell Endocrinol 2015
・「Establishment and characterization of a novel orthotopic mouse model for human uterine sarcoma with different metastatic potentials」Cancer Lett 2015
・「C/EBPβ (CCAAT/enhancer-binding protein β) mediates progesterone production through transcriptional regulation in cooperation with SF-1 (steroidogenic factor-1)」Biochem J 2014
・「Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis」FASEB J 2013
・「Nuclear receptor 5A (NR5A) family regulates 5-aminolevulinic acid synthase 1 (ALAS1) gene expression in steroidogenic cells」Endocrinology 2012
・「Identification of a novel distal control region upstream of the human steroidogenic acute regulatory protein (StAR) gene that participates in SF-1 dependent chromatin architecture」J Biol Chem 2010

Community Engagement

Committee Member of The Japan Endocrine Society
Committee Member of Japan Society of Reproductive Endocrinology

Educational Activites

Classes Anatomy and Physiology I
Anatomy and Physiology II
Graduation Study
Office Hour
Available Topics Ovary, Placenta, Transcriptional regulation, Epigenetics

Additional Information

2015 Research Award (The Japan Endocrine Society)
2001 Young investigator awards (The Japan Endocrine Society)
2001 Young scientist awards (Japan Society of Reproductive Endocrinology)